A fume hood is not mandatory, this ain't a science lab, just don't be stupid, don't inhale the fumes. (desk fans!)
Wear glasses of some kind to prevent the eyes getting crispy. If you can't afford a pair of sunglasses, but you can afford a soldering station, then you might wanna adjust your priorites. Anyways, if you don't have safety glasses, some alternatives are the Safety Squints, or the Safety Dance.
Try and keep things from setting on fire, and solder away from the smoke alarm, if you don't have a fan.
Wash your hands, dumbass. Lead poisoning isn't good.
Spongey sponges are your friend!
*I'm not responsible for the shit you get yourself into, half of this is a joke, and the other half wasn't researched properly. Learn on the job, or better yet, don't be an idiot.